Test Method of the Week – ISO 18184

Determination of antiviral activity of textile products

ISO 18184 determines the antiviral activity of treated textile products such as woven and knitted fabrics, fibres and yarns. In the procedure, a viral suspension is inoculated onto treated and untreated test articles for a specified contact time. Following incubation, the amount of virus surviving on the test article is quantified and the antiviral activity value calculated. In 2024 Virologica became the first company in the UK to hold a ISO 17025:2017 accreditation from UKAS for this method, for the two listed viruses. 

  • Required viruses: Influenza A (enveloped) and Feline calicivirus (non-enveloped). Feline calicivirus is used as a surrogate for Norovirus. Other viruses available on request.
  • Sample requirements: 9 control specimens and 6 antiviral specimens (sterile)
  • Contact time: 2 hours, may be varied but no longer than 24 hours
  • End point: TCID50
  • Efficacy: Antiviral efficacy value (Mv) 3.0 > Mv ≥ 2.0 = good effect, Mv ≥ 3.0 = excellent effect

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